Generation of an alpaca-derived nanobody recognizing γ-H2AX
نویسندگان
چکیده
منابع مشابه
Generation of an alpaca-derived nanobody recognizing γ-H2AX
Post-translational modifications are difficult to visualize in living cells and are conveniently analyzed using antibodies. Single-chain antibody fragments derived from alpacas and called nanobodies can be expressed and bind to the target antigenic sites in living cells. As a proof of concept, we generated and characterized nanobodies against the commonly used biomarker for DNA double strand br...
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ژورنال
عنوان ژورنال: FEBS Open Bio
سال: 2015
ISSN: 2211-5463
DOI: 10.1016/j.fob.2015.09.005